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April 7, 2011 /  Nivea

The Self-Made Eye

Developmental processes are increasingly well-characterized at the molecular and cell biological levels, but how more complex tissues and organs involving the coordinated action of multiple cell types in three dimensions is achieved remains something of a black box. One question of particular interest and importance is whether signaling interactions between neighboring tissues are essential to guiding organogenesis, or whether these can arise autonomously from developmental routines inherent to a given primordial tissue.

via The Self-Made Eye: Formation of Optic Cup from Embryonic Stem Cells

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